Hot-melt extrusion

Abstract In this work, real-time optimization (RTO) schemes are proposed and applied on a continuous pharmaceutical manufacturing process which consists...

Abstract MUPS (multiple unit particle systems) are oral dosage forms consisting of small particles which are filled into capsules or...

Abstract This review investigates the progression and effectiveness of colon-targeted drug delivery systems, offering a comprehensive understanding of the colon's...

In this work, a novel tool for small-scale filament production is presented. Unlike traditional methods such as hot melt extrusion...

Abstract Over the last 15 years, a small number of paediatric artemisinin-based combination therapy products have been marketed. These included Riamet®...

This poster was presented at EuPFI 2024 in Rotterdam. Introduction Loratadine, an antihistamine medication, is widely prescribed for the treatment...

Abstract Interest in Twin Screw Melt Granulation (TSMG) processes is rapidly increasing, along with the search for suitable excipients. This...

Abstract The Theophylline and Salbutamol Bilayer Sustained-release Tablets (Yi Xi Qing®), prepared via wet granulation, discolor during long-term storage, and...

Improving the solubility of poorly water-soluble drugs is essential for enhancing bioavailability, formulation flexibility and reducing patient-to-patient variability. The preparation...

Abstract Hot melt extrusion (HME) has been widely used as a continuous and highly flexible pharmaceutical manufacturing process for the...