Hydroxypropyl methylcellulose acetate succinate (HPMCAS)

Binary co-amorphous systems (CAMS) are a type of solid dispersion containing an active pharmaceutical ingredient (API) and small molecule excipients....

The in-situ formation of nanoparticles from polymer-based solid medicines, although previously described, has been overlooked despite its potential to interfere...

Low oral absorption and extensive first pass metabolism of progesterone is reported for many oral formulations which warrants investigation into...

The use of amorphous solid dispersions (ASDs) is one commonly applied formulation strategy to improve the oral bioavailability of poorly...

Hot melt extrusion (HME) technology was introduced to pharmaceuticals in the 1970s for manufacturing and product development. Since then, there...

Spray drying is one of the most frequently used solvent-based processes for manufacturing amorphous solid dispersions (ASDs). However, the resulting...

Amorphous solid dispersion (ASD) is one of the most important strategies to improve the solubility and dissolution rate of poorly...

PROteolysis TArgeting Chimaeras (PROTACs) offer new opportunities in modern medicine by targeting proteins that are undruggable to classic inhibitors. However,...

Pharmaceutical amorphous solid dispersions (ASDs) represent a widely used technology to increase the bioavailability of active pharmaceutical ingredients (APIs). ASDs...

Despite poor absorption properties, delivery to the colon of bioactive compounds administered by the oral route has become a focus...