Pharma Excipients
Inorganic Chemicals
Characterization and Exploration of Placket–Burman-Designed Porous Calcium Carbonate (Vaterite)…
The objective of the research was to identify significant variables that impact the porosity-related properties of CaCO3 particles. The Placket–Burman design was employed to screen multiple variables, including pH, molar concentrations of calcium chloride and sodium carbonate, temperature,…
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Exploring Environmental Settings to Improve the Printability of Paroxetine-Loaded Filaments by Fused…
The successful integration of hot-melt extrusion (HME) and fused deposition modelling (FDM) depends on a better understanding of the impact of environmental conditions on the printability of formulations, since they significantly affect the properties of the raw materials, whose control is crucial…
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Tableting properties of freeze-dried trehalose: physico-chemical and mechanical investigation
Abstract
Freeze-drying of biopharmaceutical products is the method of choice in order to improve their stability and storage conditions. Such Freeze-dried products are usually intended for parenteral route administration. However, many biopharmaceutical materials administered by parenteral route…
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Functionalized calcium carbonate (FCC) as a novel carrier to solidify supersaturated…
Abstract
Functionalized calcium carbonate (FCC), a novel pharmaceutical excipient, has shown promising properties in the field of oral drug delivery. The current study aimed at evaluating the feasibility of FCC as a carrier for the solidification of self-nanoemulsifying drug delivery systems…
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Image-based simultaneous particle size distribution and concentration measurement of powder blend…
Abstract
This work presents a system, where deep learning was used on images captured with a digital camera to simultaneously determine the API concentration and the particle size distribution (PSD) of two components of a powder blend. The blend consisted of acetylsalicylic acid (ASA) and calcium…
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Solid dispersion technology with porous material – Telmisartan
1. Introduction
Solid dispersion is one of the most effective technologies to improve API characteristics such as solubility, stability, and compressibility. Recently developed small molecule APIs with the aim to higher therapeutic effects, tend to become poor soluble, as much as 70% or higher…
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Transform Liquid-form Active Ingredient into Powder form with High Performance Liquid Carrier
Introduction
Several major active ingredients for human health, such as vitamin A/D/E/K, DHA/EPA, and natural herbal
extracts are supplied in liquid form. Emulsified powder and microencapsulation were previously known as the
major ways to provide better compatibility with other ingredients, but…
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Tableting of liquid form active ingredient with high performance liquid carrier
1. Introduction
Many liquid active ingredients are supplied in a soft-gel capsule form, because a soft gel capsule is easy to release control and can avoid formulation difficulties. However, it has serious weakness in stability, especially in humid environments; swallowability in the elder people,…
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Electrospun metal–organic frameworks-loaded nanofibrous carriers for drug delivery systems
Nanotechnology-based-drug-delivery processes are widely applicable for specific drug release. Various pharmaceutical carriers, such as polymeric nano-carriers (solid lipid nanoparticles, micelles, nano-gels/hydrogels, dendrimers, polymeric nano-shapes), vesicular carriers (liposome, noisome),…
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Omya mineral solutions: Easy formulation with multiple benefits
PRESS RELEASE
Oftringen (Switzerland), September 2023 – Manufacturers in the field of pharma and nutraceuticals can step into a new era of uncomplicated and future-proof formulation: With the Omyanutra® range, Suisse mineral expert Omya offers advanced excipients to overcome the challenge of…
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