Evolution of the Microstructure of Sustained-release Matrix Tablets during Dissolution and Storage

5. December 2018

Glyceryl behenate based-matrix tablets allowed obtaining a sustained release of theophylline for up to 12 hours. The diluent selected as...

Lipid nanocapsules decorated and loaded with cannabidiol as targeted prolonged release carriers for glioma therapy: in vitro screening of critical parameters

28. November 2018

The therapeutic potential of cannabinoids has been truly constrained heretofore due to their strong psychoactive effects and their high lipophilicity....

Sustained or modified release matrices at SR tablets

Excipients for Modified Release by Gattefossé

18. November 2018

Modified- or sustained-release matrices are designed to release a drug slowly over an extended period of time. Formulations must be...

Polymer-lipid hybrid nanoparticles used for carbamazepine oral delivery

Rethinking carbamazepine oral delivery using polymer-lipid hybrid nanoparticles

18. November 2018

Epilepsy is the most common chronic brain disorder and affects millions of people worldwide. Carbamazepine (CBZ) is one of the...

Drug supersaturation during fprmulation digestion, including real-time analytical approaches

Drug supersaturation during formulation digestion, including real-time analytical approaches

18. November 2018

Self-emulsifying and other lipid-based drug delivery systems have drawn considerable interest from pharmaceutical scientists for managing oral delivery of poorly...

Optimize transdermal amlodipine nanostructured lipid carriers using lipid blends

Formulation of amlodipine nano lipid carriers

17. November 2018

The present work was designed to formulate and statistically optimize transdermal amlodipine nanostructured lipid carriers (AMNLCs) using lipid blends. The...

An Overview of 3D Printing Technologies for Soft Materials and Potential Opportunities for Lipid-based Drug Delivery Systems

15. November 2018

Three-dimensional printing (3DP) is a rapidly growing additive manufacturing process and it is predicted that the technology will transform the...

Enhancing the Oral Absorption of Kinase Inhibitors Using Lipid-Based Formulations

Enhancing the Oral Absorption of Kinase Inhibitors Using Lipophilic Salts and Lipid-Based Formulations

14. November 2018

The absolute bioavailability of many small molecule kinase inhibitors (smKIs) is low. The reasons for low bioavailability are multifaceted and...

Chart of lipid nanoparticles and hydrogel composites for drug delivery

Lipid Nanoparticles and Their Hydrogel Composites for Drug Delivery: A Review

11. November 2018

Several drug delivery systems already exist for the encapsulation and subsequent release of lipophilic drugs that are well described in...

Chart about hot-melt extruded lipidic pellets

Hot-melt extruded lipidic pellets for pediatric applications: An investigation of the effects and stability on drug dissolution

1. November 2018

The current study investigates the development of extemporaneous preparation of hot melt extruded diclofenac sodium (Df-Na) pellets processed with glyceryl...

Lipids