Development of Oral Tablets of Nebivolol with Improved Dissolution Properties, Based on Its Combinations with Cyclodextrins

31. May 2024

Abstract New oral tablets of nebivolol have been developed aiming to improve, by cyclodextrin (CD) complexation, its low solubility/dissolution properties—the...

Pre-Formulation, Formulation and Pilot Scale-Up Studies to Establish the Qualitative and Quantitative Composition of an Innovative Nanoform Dietary Supplement for Menopausal Therapy

29. May 2024

The present study aimed to establish the theoretical qualitative and quantitative formula of a nanoparticle-based dietary supplement suitable for menopause...

Design and development of a chitosan-based nasal powder of dimethyl fumarate-cyclodextrin binary systems aimed at nose-to-brain administration. A stability study

25. May 2024

The nasal administration route has been studied for the delivery of active molecules directed to the Central Nervous System, thanks...

Opportunities and Challenges: Process Raman for the Real-Time Release Testing (RTRT) of Extended-Release Formulations

22. May 2024

Abstract The use of a process analytical technology has been demonstrated using near-infrared spectroscopy for continuous manufacturing of pharmaceutical formulations...

Enabling Stable and Directly Compressible Probiotic Tablet Formulations with a Novel Co-processed Mannitol-Starch Excipient

19. May 2024

This case study was presented at the 14th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, 18 - 21 March...

Formulation development, in-vitro and ex-vivo evaluation of dry adsorbed solid lipid nanoparticles: an approach of overcoming olanzapine drawbacks

1. May 2024

Abstract Aim: The present study was aimed at preparing stable dry adsorbed nanoparticles (DANs) of olanzapine (OLZ) loaded solid lipid...

Investigation on the Combined Effect of Hydroxypropyl Beta-Cyclodextrin (HPβCD) and Polysorbate in Monoclonal Antibody Formulation

26. April 2024

Monoclonal antibodies require careful formulation due to their inherent stability limitations. Polysorbates are commonly used to stabilize mAbs, but they...

Novel fast dissolving freeze dried sublingual baicalin tablets for enhanced hepatoprotective effect: in-vitro characterization, cell viability, and in-vivo evaluation

23. April 2024

Baicalin (BG), a natural product, has been used in the prevention and treatment of drug-induced liver injury (DILI); however, its...

Figure 2. GTman; tablet hardness function of compression force at increasing sertraline ratio without precompression.

Benefits of an Optimal Tabletability DC Mannitol on Compression Setting Parameters

22. April 2024

This case study was presented at the 14th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, 18 - 21 March...

Figure 2: Tablet hardness vs compression force at increasing sertraline ratio with precompression force.

Optimizing API Load and Minimizing Tablet Weight Leveraging an Innovative DC Mannitol

19. April 2024

Presented at the 14th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical (PBP) Technology, 18 - 21 March 2024, Vienna, Austria:...

Mannitol