Pediatric-friendly suspension for oral administration of pyrimethamine in congenital toxoplasmosis: Development and in use-stability study
Abstract
This study focused on developing and assessing the stability of pyrimethamine (PYM) sugar-free oral suspensions for treating congenital toxoplasmosis in the pediatric population, including neonates. Extemporaneous suspensions (2 mg/mL) were prepared using carboxymethylcellulose (CMC) or xanthan gum (XG) as suspending agents and…