HiCel HFS aids simplify multi-excipient formulations for ODTs
Struggling with complex multi-excipient formulations for Orally Disintegrating Tablets (ODTs)?
Look no further than HiCel HFS!
This coprocessed excipient combines the best of worlds of following excipients:
- Versatility of Microcrystalline Cellulose (MCC): Ensures excellent compactibility and stability for robust ODTs.
- Mouthfeel of Mannitol: Provides a pleasant dissolving experience, crucial for patient acceptance.
- Flowability of Colloidal Silicon Dioxide: Guarantees smooth processing and reduced manufacturing complexities.
HiCel HFS isn’t just about convenience; it offers tangible benefits for both manufacturers and patients:
- One Excipient, Multiple Functions: Simplify your formulation by replacing multiple ingredients with a single, reliable solution.
- Streamlined Manufacturing: Reduce processing steps and quality control tests, optimizing production efficiency.
- Miniaturized Dosage Forms: Develop smaller, easier-to-swallow ODTs, catering to patients with dysphagia and improving medication adherence.
HiCel HFS is truly a game-changer for the ODT landscape.
– Sigachi –
HiCel HFS Composition:
Microcrystalline cellulose, Colloidal silicon dioxide and Mannitol. HiCel HFS is a combination of three pharmacopeial excipients, Microcrystalline Cellulose, Colloidal Silicone Dioxide, and Mannitol. It has excellent flow properties which help to achieve uniform weight and drug content in tablets throughout the batch. HiCel HFS gives higher tablet hardness as compared to other excipients. HiCel HFS combination is suitable for moisture-sensitive drugs, it helps to protect API from moisture.
With HiCel HFS easy to switch on direct compression from the wet granulation method, because it has superior flowability with higher compressibility.
Benefits of using HiCel HFS:
- Outstanding Flow
- Excellent compatibility
- Enhanced lubrication efficiency
- Improved blending properties
- Suitable for moisture-sensitive API’s
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Source: Sigachi