Ocular Delivery

This review highlights the application of lipid nanoparticles (Solid Lipid Nanoparticles, Nanostructured Lipid Carriers, or Lipid Drug Conjugates) as effective...

Due to the rapid clearance of external agents from the surface of the cornea, conventional ocular formulations usually require frequent...

One of the major impediments to drug development is low aqueous solubility and thus poor bioavailability, which leads to insufficient...

The rationale of this study was to formulate topically effective sustained release ophthalmic Methazolamide (MTA) liposomal in-situ gel. Lipid film hydration method...

Dry eye disease (DED) represents a major public health issue worldwide. Conventional ophthalmic preparations usually have a short pre-corneal residence...

Nanoemulsions are considered as the most promising solution to improve the delivery of ophthalmic drugs. The design of ophthalmic nanoemulsions...

Vancomycin (VCM) is a drug of choice for treating infections caused by Staphylococcus species, reported being the most causative agent of bacterial...

The influence of macromolecules in major eye disorders including retinal neovascularization, retinopathy, age-related macular degeneration, choroidal neovascularization, etc. offers substantial advantages in the...

Levofloxacin (LVF) is an antibacterial drug approved for the treatment of ocular infections. However, due to the low ocular bioavailability,...

Dry eye disease (DED) or keratoconjunctivitis sicca is a chronic multifactorial disorder of the ocular surface caused by tear film...