Nanostructured lipid carriers as a novel tool to deliver sclareol: physicochemical characterisation and evaluation in human canc

FTIR spectra of SC, Compritol® 888 ATO, SLN-SC, and NLC-SC. The area circled highlights the difference in the absorption bands between Compritol® 888 ATO and the nanocarriers (SLN-SC and NLC-SC)

Nanostructured lipid carriers as a novel tool to deliver sclareol: physicochemical characterisation and evaluation in human cancer cell lines

7. October 2021

Sclareol (SC) is arousing great interest due to its cytostatic and cytotoxic activities in several cancer cell lines. However, its...

Self-assembled tacrolimus-loaded lecithin-chitosan hybrid nanoparticles for in vivo management of psoriasis

1. October 2021

Lecithin-chitosan hybrid nanoparticles are emerging as a promising nanocarrier for topical drug delivery. They could achieve a maximized encapsulation of hydrophobic drugs due to the lipophilic...

Encapsulating cannabinoids in lipid-based nanoparticles: THC vs. CBD – Part 2 of the series

30. September 2021

Enhancing cannabinoids’ therapeutic efficacy In our previous technical note, we reported on the encapsulation of CBD vs CBDA (1). The...

Spray (micro) encapsulation of sensitive substances in matrix form: An overview of essential oil and vitamin case studies

16. September 2021

Phytochemicals are increasingly found in many food, chemical and agricultural items. Product and process optimization is becoming ever-more important in...

graphical abstract of Enhanced oral bioavailability of rutin by a self-emulsifying drug delivery system of an extract of calyces from Physalis peruviana

Enhanced oral bioavailability of rutin by a self-emulsifying drug delivery system of an extract of calyces from Physalis peruviana

10. September 2021

The aim of this study was to develop and optimize a self-emulsifying drug delivery system (SEDDS) containing an extract of...

graphical abstract of Lactose-Gated Mesoporous Silica Particles for Intestinal Controlled Delivery of Essential Oil Components: An In Vitro and In Vivo Study

Lactose-Gated Mesoporous Silica Particles for Intestinal Controlled Delivery of Essential Oil Components: An In Vitro and In Vivo Study

8. September 2021

Mesoporous silica microparticles functionalized with lactose for the specific release of essential oil components (EOCs) in the small intestine are...

graphical abstract of Formulation design, production and characterisation of solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) for the encapsulation of a model hydrophobic active

Formulation design, production and characterisation of solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) for the encapsulation of a model hydrophobic active

7. September 2021

Lipid nanoparticles have been widely investigated for their use as either carriers for poorly water soluble actives or as (Pickering)...

Inclusion of Medium-Chain Triglyceride in Lipid-Based Formulation of Cannabidiol Facilitates Micellar Solubilization In Vitro, but In Vivo Performance Remains Superior with Pure Sesame Oil Vehicle

2. September 2021

Oral sesame oil-based formulation facilitates the delivery of poorly water-soluble drug cannabidiol (CBD) to the lymphatic system and blood circulation....

Comparison of Three Different Aqueous Microenvironments for Enhancing Oral Bioavailability of Sildenafil: Solid Self-Nanoemulsifying Drug Delivery System, Amorphous Microspheres and Crystalline Microspheres

31. August 2021

Background: The purpose of this study was to screen various drug delivery systems for improving the aqueous solubility and oral bioavailability...

Self-dispersing self-assembling systems for controlled oral delivery of gliclazide

24. August 2021

Self-microemulsifying systems undergo self-dispersion to form microemulsion with subsequent self-assembly to form liquid crystalline (LC) and/or gel phases. These transitions...

Pharmaceutical Oils

Nanostructured lipid carriers as a novel tool to deliver sclareol: physicochemical characterisation and evaluation in human cancer cell lines

Self-assembled tacrolimus-loaded lecithin-chitosan hybrid nanoparticles for in vivo management of psoriasis

Encapsulating cannabinoids in lipid-based nanoparticles: THC vs. CBD – Part 2 of the series

Spray (micro) encapsulation of sensitive substances in matrix form: An overview of essential oil and vitamin case studies

Enhanced oral bioavailability of rutin by a self-emulsifying drug delivery system of an extract of calyces from Physalis peruviana

Lactose-Gated Mesoporous Silica Particles for Intestinal Controlled Delivery of Essential Oil Components: An In Vitro and In Vivo Study

Formulation design, production and characterisation of solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) for the encapsulation of a model hydrophobic active

Inclusion of Medium-Chain Triglyceride in Lipid-Based Formulation of Cannabidiol Facilitates Micellar Solubilization In Vitro, but In Vivo Performance Remains Superior with Pure Sesame Oil Vehicle

Comparison of Three Different Aqueous Microenvironments for Enhancing Oral Bioavailability of Sildenafil: Solid Self-Nanoemulsifying Drug Delivery System, Amorphous Microspheres and Crystalline Microspheres

Self-dispersing self-assembling systems for controlled oral delivery of gliclazide

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