Oral Excipients

Although protein drugs are powerful biologic therapeutics, they cannot be delivered orally because their large size and hydrophilicity limit their...

Cosolvent and polyethylene glycol (PEG)-based solubilization techniques for the delivery of poorly soluble drugs are discussed in this chapter. The...

Controlling hyperglycemia and avoiding glucose reabsorption are significant goals in type 2 diabetes treatments. Among the numerous modes of medication...

It is now recognized that a number of excipients previously considered to be “inert” have the capacity to alter drug...

Current study aimed to develop a spray-dried powder containing indomethacin (IND)-loaded polymeric micelles which can be administered perorally as a...

The present study focuses on the compaction behavior of polymeric excipients during compression in comparison to nonpolymeric excipients and its...

Recently, minitablets have been given extensive coverage in literature, as they are perfectly matched to the current therapy individualization trend....

The low oral bioavailability, short biological half-life, high dose, and frequent dosing of berberine (BBR) contribute to its restricted clinical...

There is a growing interest in the use of melatonin in preventing radiation-induced mucositis with potential beneficial effects including prevention...

Individual dosing of pharmaceutics and personalized medicine have become important with regard to therapeutic safety. Dose adjustments, biorelevant drug release...