Oral Excipients

The aim of this study was to fabricate nanostructured lipid carriers, NLCs, of nintedanib (BIBF) to improve its oral bioavailability....

Fixed-dose combination (FDC) products containing at least two different active pharmaceutical ingredients are designed to treat more effectively different pathologies...

Oral application of drugs is not only the most common way for systemic drug application, it is also patient’s route...

Felodipine (FLD), a dihydropyridine calcium channel blocker with excellent antihypertensive effect, is poorly soluble and undergoes extensive hepatic metabolism, which...

Classified as a Biopharmaceutical Classification System (BCS) class IV drug, amphotericin B (AmB) has low aqueous solubility and low permeability...

The aim of this work was to evaluate the effectiveness of mesoporous clays or silicas to develop fast-dissolving glyburide tablets...

The aim of the present paper is to study the effect of common excipients on the permeability of atenolol (as...

In its 33 years, ADDR has published regularly on the potential of oral delivery of biologics especially peptides and proteins. In...

Disintegration is the first event in the bioavailability cascade after the ingestion of immediate release tablets. Although the influence of...

Wetting is the initial stage of wet granulation processes during which the first contact between the powder and the liquid...