In-situ forming solvent-induced phase inversion (SIPI) implants for controlled drug delivery: role of hydrophilic polymers

19. March 2025

In recent years, there has been a surge of research focused on in situ-forming implants as a method of localized...

3D Printing of Tailored Veterinary Dual-Release Tablets: A Semi- Solid Extrusion Approach for Metoclopramide

16. March 2025

Abstract Metoclopramide (MCP) is frequently used to control nausea and vomiting in animals, but its short half-life requires it to...

Advancements in Colon-Targeted Drug Delivery: A Comprehensive Review on Recent Techniques with Emphasis on Hot-Melt Extrusion and 3D Printing Technologies

7. November 2024

Abstract This review investigates the progression and effectiveness of colon-targeted drug delivery systems, offering a comprehensive understanding of the colon's...

The Role of Coatings and Plasticizers Compatibility in Stability of Advanced Gastro-resistant Self-emulsifying Pellets Designed for the Delivery of Volatile Compounds: A Combined Solid-State NMR and Dissolution Study

6. November 2024

The gastro-resistant behaviour of solid self-emulsifying drug delivery systems (S-SEDDS) represents a significant and innovative advancement in delivering poorly soluble...

Impact of Hot-Melt Extrusion on Glibenclamide’s Physical and Chemical States and Dissolution Behavior: Case Studies with Three Polymer Blend Matrices

29. August 2024

Abstract This research work dives into the complexity of hot-melt extrusion (HME) and its influence on drug stability, focusing on...

Figure 1: General preparation method of film-forming sprays

Fungal Infections: Effect of Eudragit RL-100 Based Miconazole Film Forming Spray

19. July 2024

ABSTRACT Background: Miconazole nitrate, a BCS class II drug which is used for treatment of fungal infections. To minimize the...

Colon targeting in rats, dogs and IBD patients with species-independent film coatings

9. July 2024

Polysaccharides were identified, which allow for colon targeting in human Inflammatory Bowel Disease (IBD) patients, as well as in rats...

Stability of Dexamethasone during Hot-Melt Extrusion of Filaments based on Eudragit® RS, Ethyl Cellulose and Polyethylene Oxide

4. July 2024

Hot-melt extrusion (HME) potentially coupled with 3D printing is a promising technique for the manufacturing of dosage forms such as...

An emerging terpolymeric nanoparticle pore former as an internal recrystallization inhibitor of celecoxib in controlled release amorphous solid dispersion beads: Experimental studies and molecular dynamics analysis

30. June 2024

Solid oral controlled release formulations feature numerous clinical advantages for drug candidates with adequate solubility and dissolution rate. However, most...

Quality by design approach for fabrication of extended-release buccal films for xerostomia employing hot-melt extrusion technology

20. June 2024

The study endeavors the fabrication of extended-release adipic acid (APA) buccal films employing a quality by design (QbD) approach. The...

Ethyl Cellulose