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Ethyl Cellulose
Binder jetting 3D printing of challenging medicines: from low dose tablets to hydrophobic molecules
Increasing access to additive manufacturing technologies utilising easily available desktop devices opened novel ways for formulation of personalized medicines. It is, however, challenging to propose a flexible and robust formulation platform which can be used for fabrication of tailored solid…
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Optimization and Scale-up Methodology in Preparing Microsponge Loaded with 5-Fluorouracil (5-FU).
The present investigation aims at developing models by response surface methodology (FCCCD) followed by the scale-up method in preparing control release microsponge particles loaded with 5- fluorouracil, a drug used to treat actinic keratosis and colon cancer, and producing a new Dermal Delivery…
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Formulation development and in-vitro evaluation of dexlansoprazole loaded double walled microspheres
In the present work, double walled microspheres of Dexlansoprazole using Sodium alginate, HPMC E15, Xanthan gum, Ethyl cellulose as copolymers and along with Carbopol were formulated to deliver Dexlansoprazole through oral route. Details regarding the preparation and evaluation of the formulations…
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New Characterization Measures of Pore Shape and Connectivity Applied to Coatings used for Controlled…
Pore geometry characterization-methods are important tools for understanding how pore structure influences properties such as transport through a porous material. Bottlenecks can have a large influence on transport and related properties. However, existing methods only catch certain types of…
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Polymeric Drug Delivery Systems by Additive Manufacturing
Additive manufacturing (AM) is gaining interests in drug delivery applications, offering innovative opportunities for the design and development of systems with complex geometry and programmed controlled release profile. In addition, polymer-based drug delivery systems can improve drug safety and…
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Formulate and Evaluate Famciclovir Floating Tablets
Floating drug delivery system of famciclovir was developed to prolong gastric residence time, target stomach mucosa and increase drug bioavailability by using different polymers like HPMC E15, Xanthan gum, methyl cellulose and compritol 888 ATO with different concentration. Famciclovir capable of…
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3D Printed Pellets (Miniprintlets): A Novel, Multi-Drug, Controlled Release Platform Technology
Winner of the Pharmaceutics 2021 Best Paper Awards
Selective laser sintering (SLS) is a single-step three-dimensional printing (3DP) process that can be leveraged to engineer a wide array of drug delivery systems. The aim of this work was to utilise SLS 3DP, for the first time, to produce small…
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Opportunities and challenges of three-dimensional printing technology in pharmaceutical formulation…
Three-dimensional printing (3D-printing) is a technology that prints the products layer-by-layer, in which materials are deposited according to the digital model designed by computer aided design (CAD) software. This technology has competitive advantages regarding product design complexity, product…
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3DP Printing of Oral Solid Formulations: A Systematic Review
Three-dimensional (3D) printing is a recent technology, which gives the possibility to manufacture personalised dosage forms and it has a broad range of applications. One of the most developed, it is the manufacture of oral solid dosage and the four 3DP techniques which have been more used for their…
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Permeation and Absorption of Ethanol/Water Mixture through Ethylcellulose Film
Ethylcellulose (EC) is water-insoluble, rate-controlling polymer which has been widely used as coatings of oral solid dosage forms, excipients for amorphous solid dispersions of active pharmaceutical ingredients (APIs), and films for buccal and transdermal drug delivery systems. The interaction of…
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