Trehalose

Join our inspiring expert talk on Trehalose Enhances Removal:  Description: In this study, adding trehalose during CHO cell harvest resulted...

Abstract Polymeric micelles are promising nanocarriers for improving the solubility and therapeutic efficacy of poorly water-soluble drugs. In this study,...

Abstract Background: Despite the growing importance of polypeptide-based drugs in clinical therapy, studies investigating the stability of their freeze-dried formulations...

World’s First Mass Production Through Enzyme Innovation Trehalose (α-D-glucopyranosyl α-D-glucopyranoside) is a naturally occurring disaccharide prized for its ability to...

Abstract Formulation development of protein biopharmaceuticals has become increasingly challenging due to new modalities and higher target drug substance concentrations....

Abstract Biopharmaceutical medicines represent one of the most dynamic sectors of the pharmaceutical industry, with therapeutic proteins forming the largest...

Abstract Surface adsorption of proteins in bulk drug product formulations and loss of protein structural integrity during manufacturing processes can...

Abstract The transdermal delivery of large molecules such as proteins and vaccines faces enormous challenges and at the same time...

Abstract Lyophilization enhances mRNA vaccine stability, but conventional approaches using external trehalose for lipid nanoparticle (LNP) colloidal stability neglect mRNA...

Abstract Posaconazole (PCZ) is a broad spectrum anti-fungal drug approved by FDA and currently used off-label for the treatment of...