Studies on the in vitro ion exchange kinetics and thermodynamics and in vivo pharmacokinetics of the carbinoxamine-resin complex

20. August 2020

The short half-life and bitter taste of carbinoxamine maleate (CAM) lead to poor compliance by pediatric patients who are being...

A Novel Oral Syringe for Dosing and Administration of Multiparticulate Formulations: Acceptability Study in Preschool and School Children

12. August 2020

The popularity of multiparticulate formulations (MPs) as a paediatric dosage form continues to increase. MPs comprise of multiple small units...

Orphan Formulations for Pediatric Use: Development and Stability Control of Two Sildenafil Citrate Solutions for the Treatment of Pulmonary Hypertension

8. August 2020

Sildenafil citrate causes vasodilatation, relaxation of the smooth muscle, and reduction of pulmonary arterial pressure. The latter property makes sildenafil...

The PDCA cycle of the reformulation work

Effects of Formulation Excipients on Skin Barrier Function in Creams Used in Pediatric Care

6. August 2020

Semisolid dosage forms are recommended for the dermal care of babies and children. If we look at the ingredients of...

Comparison of Different Liquid and Semisolid Vehicles Selected for Oral Administration of Pellets and Minitablets with Diazepam: In Vitro Investigation

6. August 2020

The acceptability and palatability of a dosage form are extremely important to improve patient compliance. Mixing oral solid dosage forms...

3D printed gummies: Personalized drug dosage in a safe and appealing way

2. August 2020

Obtention of customized dosage forms is one of the main attractions of 3D printing in pharmaceuticals. In this sense, children...

Development of a stable oral pediatric solution of hydrochlorothiazide by the combined use of cyclodextrins and hydrophilic polymers

29. July 2020

Hydrochlorothiazide (HCT) is widely used in pediatrics for hypertension management. Due to the lack of pediatric commercial forms, community or...

Paediatric