Polysorbates

Abstract Lipid-based drug delivery systems are very promising in addressing critical medical needs associated with cancer because they are able...

Abstract A tunable modular design (TMD) as a new approach was proposed to tailor the dose and drug release profile...

Abstract Formulation development of protein biopharmaceuticals has become increasingly challenging due to new modalities and higher desired drug substance concentrations....

Abstract This study explores the potential of spectroscopic analysis combined with Partial Least Squares Regression (PLS) and Multivariate Curve Resolution-Alternating...

Abstract This study developed a solid self-nanoemulsifying drug delivery system (S-SNEDDS) to improve the oral bioavailability of poorly soluble carvedilol...

Abstract Solid forms transformations and new crystal structures of an active pharmaceutical ingredient (API) can occur due to various manufacturing...

Abstract Pharmaceutical excipients such as P-glycoprotein inhibitors can also increase the solubility and affinity of drugs to the intestinal membrane,...

Abstract For monoclonal antibody drug products as for other biologics, while the innovator drug products first becomes commercially available, they...

Abstract Purpose: To improve the oral absorption of relugolix (RLGL), which has low oral bioavailability due to its low solubility...

Abstract Nanocrystalline formulations typically contain stabilizing additives to minimize the risk of particle growth or agglomeration. This risk is particularly...