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Gelucire 48/16

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Description

A non-ionic pure surfactant for lipid-based formulation to solubilize and increase oral bioavailability of poorly soluble API. Forms micellar solution in aqueous media.

Main functionalities: Solubilizer for low log P APIs and bioavailability enhancer. Single excipient formulation system: self-emulsifies in aqueous fluid into micellar solution—LFCS Type IV. Use in melt processes (granulation, extrusion), granulation, and compression. Wetting agent. Safety of use is inferred by precedence of use in approved pharmaceutical products.

Additional information

Manufacturer

Gattefosse
Quality

USP-NF/EP
Composition

Polyoxylethylene stearates
Dosage Form

Oral
Function

Melt processes: granulation, extrusion, capsule molding, and compression., Self-emulsifying lipid formulation for oral applications., Wet granulation and compression.

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Brochure Gelucire 48/16

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