Description
GRANFILLER-D is state-of-the-art co-processed excipient for direct compression ODTs. It is jointly developed by DAICEL Group and NICHIRIN-Chem.
It is originally designed to achieve compatibility between high tablet hardness and rapid disintegration in the direct compression method of tablet production.
Benefits and strengths
・High performance due to sophisticated co-processed formulation
・No need for special equipment, only conventional equipment
・Simple manufacturing process ( weighing, mixing, tableting …etc. )
Characteristics:
-Well balanced tablet property between orally disintegration time & hardness
-High API loading capacity
-Excellent content uniformity
-Compatible with various excipients.
Particle size: 140μm median size
Bulk density: 0.31g/cm3
Tapped density: 0.43g/cm3
Angle of repose: 39°
Orifice diameter: 4.0mm
All components of GRANFILLER-D are listed on JP, USP and EP.
Both GNF-D211 and GNF-D215 are listed on JPE2018.
GNF-D211 is listed on US-DMF and GNF-D215 will be listed next.















































