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HiSORAD HSR-D03

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Description

HiSORAD is a state-of-the-art co-processed excipient for orally disintegrating tablets designed to have well-balanced property between oral disintegration time and tablet hardness.

Composed of three compendial grade excipients, D-Mannitol, Microcrystalline cellulose and Croscarmellose sodium.

Characteristics: 

  • Excellent compactibility
  • Well-balanced tablet property between OD time and hardness
  • High API loading capacity
  • Simple composition

HiSORAD is developed for direct compression by conventional manufacturing and packaging machineries.
HiSORAD consists of excipients that have already been chosen and processed to design ODTs. In the simplest case,
manufacturers only need to mix HiSORAD with APIs and lubricants before tableting.
As it helps in the formulation of ODTs, HiSORAD can be a time-saving tool for manufacturers.

Item Typical Value
Mean Particle Size*1 106 μm
Density*2 Loose   0.35 g/cm3
Tapped   0.49 g/cm3
Angle of Repose*2 41°
Orifice Diameter*3 6.3 mm
Water Content 2.4 wt%

Measurement methods
*1 Dry laser diffraction/light scattering instrument
*2 Powder tester
*3 Orifice diameter measurement instrument

Additional information

Manufacturer

DAICEL

Quality

EP, JP, USP

Dosage Form

orally disintegrating tablets, Tablets

Function

DC Excipient, Directly compressible excipient for ODTs, Dry granulation

Composition

Croscarmellose Sodium, D-Mannitol, Microcrystalline Cellulose

Synonym

Directly compressible excipient for ODTs

Documents and Links

HiSORAD

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