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INHALAC 120

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Description

MEGGLE – high quality crystalline lactose producers, designed for DPIs

MEGGLE has developed a specialty lactose grade, InhaLac®, to help meet the challenges associated with dry powder inhalation (DPI).

Inhalation aerosols offers the potential for needle-free systemic delivery of small molecule drugs as well as therapeutic peptides and proteins.  An industry standard in dry power inhalation formulation development, lactose monohydrate is used safely in DPI formulations. Using lactose as an excipient not only improves performance efficiency of the inhaler, but also facilitates powder handling during production. Effective performance of a dry powder inhaler largely depends on the carrier material used for the drug formulation.

With our highly controlled production process different high quality sieved and milled grades are obtained, providing an adequate range of particle sizes – making them behave as individual particles.

 

Standard Packaging:
25 kg – Carton box with double PE-EVOH-PE Inliner

 

Particle size distribution [Laser diffraction]

  • DPI Lactose_excipient inhalation_sieved_120 Meshx10: 70-105 µm
  • x50: 110-155 µm
  • x90: 160-215 µm

Shelf life / Retest:
24 months

Typical Values

  • Bulk Density [g/l]: 720
  • Tapped Density [g/l] : 830
  • Hausner factor: 1.15
  • Carrs index: 13 %
Inhalac 120_Typical size

Benefits

  • Dedicated production process
  • Tailor-made products with specific powder characteristics
  • Highest microbial quality including low endotoxins
  • Available in a broad spectrum of sieve cuts to meet your criteria

Areas of Application

With InhaLac®, MEGGLE can offer customized milled and sieved fractions – specifically and efficiently prepared to meet your DPI formulation needs.

Additional information

Manufacturer

Meggle

Quality

EP, JP, USP/NF

Cas-No

5989-81-1

Composition

Lactose for Inhalation

Dosage Form

Inhalation

Function

Used for Dry Powder Inhaler formulations

Documents and Links

Brochure InhaLac_EN_2023

Download

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