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INHALAC 500

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Description

Dry powder inhalers (DPIs) are widely used in pulmonary drug delivery. This is due to their advantages, such as ease of use, small size, portability and not needing breath-actuation coordination. In addition, they are propellant-free and therefore, environmentally friendly. Furthermore, as solid-particle formulations they are comparatively stable. Commonly, this dosage form contains a device, one or more APIs and an excipient, which improves powder handling during the manufacturing process. Properties, such as particle size are fundamental factors in the design of DPI formulations.

In DPI formulations the excipient not only acts as a filler, but also contributes to the performance of the DPI. A profound knowledge about the physico-chemical properties is a prerequisite to ensure the functionality and safety of the DPI. This implies an established and well-investigated production process.

MEGGLE’s InhaLac® grades are produced via crystallization and subsequent sieving, milling or micronization.

DPI Lactose_excipient inhalation_micronized_500 MeshShelf life / Retest:
18 months

Standard Packaging:
6 kg – Carton box with aluminium laminated Inliner

Particle size distribution [Laser diffraction]

  • x10: –
  • x50: NMT 5 µm
  • x90: NMT 10 µm
Inhalac 500_Typical sizeTypical Values

  • Bulk Density [g/l]: 240
  • Tapped Density [g/l] : 370
  • Hausner factor: 1.54
  • Carrs index: 35 %

Benefits

  • Highly controlled powder characteristics
  • Highest microbial quality including endotoxines
  • Customized grades
  • Customized product specifications
Areas of Application
InhaLac® is suitable for use in pulmonary and nasal drug delivery.

Additional information

Manufacturer

Meggle

Quality

EP, JP, USP/NF

Cas-No

5989-81-1

Composition

Lactose for Inhalation

Dosage Form

Inhalation

Function

Used for Dry Powder Inhaler formulations

Documents and Links

Technical brochure InhaLac 500

Download

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