Pemulen™ TR-1 NF Polymer

Description

Pemulen™ TR-1 NF polymer is a primary oil-in-water emulsifier which can emulsify up to 20 – 30% oil by weight. It is an emulsion former, not an emulsion stabilizer like many of the Carbopol^® polymers. Pemulen TR-1 NF polymer can enable formulation of permanent emulsions at very low use levels of the polymer (less than 0.3 wt.%), even at elevated temperatures, without the use of irritating surfactants.

Emulsions based on Pemulen polymers deposit an occlusive layer on the skin, delivering the topical medication in the form of low-irritancy lotions and creams with elegant skin feel. Pemulen TR-1 NF polymer can also be used for high-clarity topical gels with ionic components.

Pemulen in general: Pemulen^™ polymeric emulsifiers are high molecular weight copolymers of acrylic acid and C10-C30 alkyl acrylate crosslinked with allyl pentaerythritol. These pharmaceutical excipients provide effective emulsification properties to form stable oil-in-water emulsions. Pemulen polymer excipients contain both hydrophilic and hydrophobic portions and serve as excellent gel forming polymers, creating a network around suspended oil droplets and providing exceptional emulsion stability, often without the need for additional surfactants.