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SORBOLAC 400

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Description

SorboLac® 400 consist of fine, sharp-edged lactose particles, having cohesive powder properties that can be beneficial during granulation processes. Clean unlubricated surfaces created during the compaction process as a result of brittle fracture lead to improved compactability.

MEGGLEs milled alpha-lactose monohydrate grades have been historically used as diluents in dry and wet granulation processes by numerous global and regional pharmaceutical manufacturers.

Shelf life / Retest:
36 months

Standard Packaging:
20 kg – Paper bag with aluminium laminated Inliner

Particle size distribution [Air jet sieve]

  • <32 µm: NLT 90%

Typical Values

  • Bulk Density [g/l]: 330
  • Tapped Density [g/l] : 590
  • Hausner factor: 1.79
  • Carrs index: 44.07 %
Milled Lactose Monohydrate_400 Mesh Lactose

Benefits

  • Good compactability
  • Narrow particle size distribution
  • Good blending properties
  • High storage stability
  • High batch-to-batch consistency
Areas of Application

  • Dry granulation
  • Wet granulation
  • Blends, premixes, sachets, triturations
  • Enhancement of flavours
  • Media for fermentation
  • Extrusion-spheronization

 

Sorbolac 400_Typical size Particle size distribution batch-to-batch consistency of SorboLac® 400 by air-jet-sieving.Data obtained from a permanent in-process-controll (IPC) of subsequent batches over a time period of 12 months.

Sorbolac 400_BatchParticle size distribution batch-to-batch consistency of SorboLac® 400 by air-jet-sieving.Data obtained from a permanent in-process-controll (IPC) of subsequent batches over a time period of 12 months.

Additional information

Manufacturer

Meggle
Quality

EP, JP, USP/NF
Cas-No

5989-81-1
Composition

Lactose Monohydrate
Dosage Form

Sachets, Tablets
Function

blends, Diluent for wet and dry granulation, extrusion spheronization, premixes, sachets and triturations

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