SEM image Meggle excipient Tablettose 70

Tablettose 70

€0.00

SKU: PE258 Category:

Description

The product Tablettose® is manufactured by a continous spray agglomeration process, where water is used as the binder and is sprayed onto fluidized fine milled lactose particles, creating liquid bridges to form agglomerated lactose.

Tablettose®, especially designed for Direct-Compression, combines the flowability of coarse lactose crystals and the good compressibility of fine milled lactose.

Tablettose® 70 is manufactured using identical starting material as Tablettose® 80; however, the particle size distribution is narrower. The content of fines smaller than 63 µm is reduced significantly and there are no particles larger than 500 µm, making Tablettose® 70 the excipient of choice for narrow particle size distribution and dust free production.

 

Shelf life / Retest:
36 months

Particle size distribution [Mechanical sieve shaker]

  • <63 µm: NMT 6%
  • <200 µm: 30-70%
  • <500 µm: NLT 98%

Standard Packaging:
20 kg – Paper bag with PE-EVOH-PE Inliner

Typical Values

  • Bulk Density [g/l]: 530
  • Tapped Density [g/l] : 640
  • Hausner factor: 1.21
  • Carrs index: 17.19 %

Agglomerated Lactose Monohydrate_70 Mesh Lactose_Direct Compression

Benefits

  • Very good flowability
  • Very good compactability
  • Low hygroscopicity
  • Excellent stability
  • Superior blending characteristics
  • Fast disintegration times

Areas of Application

  • Low dose DC formulations
  • Capsule and sachet filling
  • Effervescent tablets
  • Artificial sweetener tablets
  • Orally disintegrating tablets

 

Tablettose 70_Typical size Particle size distribution batch-to-batch consistency of Tablettose® 70 by air-jet-sieving.Data obtained from a permanent in-process-controll (IPC) of subsequent batches over a time period of 12 months.

Tablettose 70_Batch

Particle size distribution batch-to-batch consistency of Tablettose® 70 by air-jet-sieving.Data obtained from a permanent in-process-controll (IPC) of subsequent batches over a time period of 12 months.

Additional information

Manufacturer

Meggle
Quality

EP, JP, USP/NF
Composition

Agglomerated, DC Lactose
Dosage Form

Capsules, Sachets, Tablets
Function

ODT and artificial sweetener tablets. Also, used in capsules and sachet filling, Used in low dose DC formulations as well as for effervescent tablets

Technical brochure Tablettose

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