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TABLETTOSE 80

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Description

The product Tablettose® is manufactured by a continous spray agglomeration process, where water is used as the binder and is sprayed onto fluidized fine milled lactose particles, creating liquid bridges to form agglomerated lactose.

Tablettose®, especially designed for Direct-Compression, combines the flowability of coarse lactose crystals and the good compressibility of fine milled lactose.

MEGGLEs Tablettose® 80 was the first available agglomerated alpha-lactose monohydrate of its kind. Its agglomerates possess a size ranging from 0 – 630 µm.

Shelf life / Retest:
36 months
Particle size distribution [Mechanical sieve shaker]

  • <63 µm: NMT 20%
  • <180 µm: 40-75%
  • <400 µm: NLT 85%
  • <630 µm: NLT 97%

Standard Packaging:
25 kg – Paper bag with PE-EVOH-PE Inliner

Typical Values

  • Bulk Density [g/l]: 620
  • Tapped Density [g/l] : 770
  • Hausner factor: 1.24
  • Carrs index: 19.48 %
Agglomerated Lactose Monohydrate_80 Mesh Lactose_Direct Compression

Benefits

  • Very good flowability
  • Very good compactability
  • Low hygroscopicity
  • Excellent stability
  • Superior blending characteristics
  • Fast disintegration times
Areas of Application

  • Low dose DC formulations
  • Capsule and sachet filling
  • Effervescent tablets
  • Artificial sweetener tablets
  • Orally disintegrating tablets

 

Tablettose 80_Typical sizeParticle size distribution batch-to-batch consistency of Tablettose® 80 by air-jet-sieving.Data obtained from a permanent in-process-controll (IPC) of subsequent batches over a time period of 12 months.

Tablettose 80_Batch

Particle size distribution batch-to-batch consistency of Tablettose® 80 by air-jet-sieving.Data obtained from a permanent in-process-controll (IPC) of subsequent batches over a time period of 12 months.

Additional information

Manufacturer

Meggle

Quality

EP, JP, USP/NF

Composition

Agglomerated, DC Lactose

Dosage Form

Capsules, Sachets, Tablets

Function

ODT and artificial sweetener tablets. Also, used in capsules and sachet filling, Used in low dose DC formulations as well as for effervescent tablets

Documents and Links

Technical brochure Tablettose

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