Sodium Stearyl Fumarate

Abstract Objectives: The current study presents a sequential strategy for the development of directly compressible powder formulations relying on Design...

Abstract Purpose This research was designed to systematically investigate the performance of three lactose-based co-processed excipients (CPEs): SuperTab® 40LL, StarLac®, and...

Abstract Background/Objectives: Poor aqueous solubility of active pharmaceutical ingredients (APIs) remains a critical barrier to effective oral formulation. This study...

Formulation Challenges in Low-Dose Fixed-Dose Combinations Developing fixed-dose combination (FDC) therapies presents unique formulation challenges, particularly when one active pharmaceutical...

Abstract The presented work investigates critical aspects of rational formulation design through machine learning (ML) methodology to identify essential patterns...

Abstract Background: The compaction of formulation blends is a critical stage in pharmaceutical tablet manufacturing, particularly when drug substances or...

PMC Isochem, have developed four Vitamin E TPGS premixes ( see the brochure below) with 4 common excipients used as...

Abstract Silicification of microcrystalline cellulose (MCC) has previously been shown to have positive effects on the powder’s flowability and tabletability...

Abstract Granulation is a major focus of pharmaceutical R&D, as a key step in the development of solid pharmaceuticals. In...

Abstract Objectives The study aimed to combine instant-release and mini-tablet methodologies to develop novel orally disintegrating mini-tablets (ODMTs) for a...