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The objective of this study was to enhance dissolution and permeation of a low soluble, absorbable fexofenadine hydrochloride (FFH) by...
Amorphous solid dispersions (ASDs) are a promising drug-delivery strategy to overcome poor solubility through formulation. Currently, the understanding of drug...
Silymarin is a mixture of flavonolignans obtained from the seeds of milk thistle (Silybum marianum L. Gaertner). Silymarin behaves as a weak acid and...
Amorphous solid dispersion (ASD) is one of the most promising formulation technologies for improving the oral absorption of poorly soluble...
Objective: Bioavailability of Meloxicam (MLX) from solid dispersions (SDs), against innovator product Mobic® in humans was conducted. Furthermore, to establish...
The hot melt extrusion (HME) technique was proposed to prepare solid dispersions (SDs) of the high melting point meloxicam (MLX)...
The term “multicomponent solid dispersion” is widely used in recent literature to describe solid formulations consisting of a special excipient's...
Soluplus is a pharmaceutical excipient used primarily in the manufacture of solid dispersions. The polymer also exhibits interesting rheology in...
05. June 2018 Due to the high number of poorly soluble drugs in the development pipeline, novel processes for delivery...
24. September 2017 Abstract The aim of this study was to evaluate a novel combination of hydroxypropyl methylcellulose phthalate (HPMCP-HP-50) and Soluplus®polymers...
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