Impact of Matrix Surface Area on Griseofulvin Release from Extrudates Prepared via Nanoextrusion

Digital microscope images showing the morphological evolution of a 10% GF-Sol (ASD) particle, a 10% GF-Kol (nanocomposite) particle, and a 10% GF-HPC (nanocomposite) particle in 3 µL deionized water. Scale bar is identical for all images: 100 µm.

Impact of Matrix Surface Area on Griseofulvin Release from Extrudates Prepared via Nanoextrusion

13. July 2021

We aimed to examine the impact of milling of extrudates prepared via nanoextrusion and the resulting matrix surface area of...

Figure 1: Enhancement strategies for drug solubility and dissolution rate.

Solid Dispersion as a Technical Solution to Boost the Dissolution Rate and Bioavailability of Poorly Water-Soluble Drugs

24. June 2021

Solid dispersion (SD) is one of the oldest and widely utilized techniques to improve the solubility of slowly dissolving drugs....

graphical abstract of Continuous downstream processing of milled electrospun fibers to tablets monitored by near-infrared and Raman spectroscopy

Continuous downstream processing of milled electrospun fibers to tablets monitored by near-infrared and Raman spectroscopy

17. June 2021

Electrospinning is a technology for manufacture of nano- and micro-sized fibers, which can enhance the dissolution properties of poorly water-soluble...

graphical abstract of Nanostructured micronized solid dispersion of crystalline-amorphous metronidazole embedded in amorphous polymer matrix prepared by nano spray drying

Nanostructured micronized solid dispersion of crystalline-amorphous metronidazole embedded in amorphous polymer matrix prepared by nano spray drying

15. June 2021

In this study metronidazole drug was encapsulated by hydroxypropyl methylcellulose and polyvinylpyrrolidone polymers from solutions using nano spray drying technology....

Phase behavior of ASDs based on hydroxypropyl cellulose

12. June 2021

Novel polymeric carriers for amorphous solid dispersions (ASDs) are highly demanded in pharmaceutical industry to improve the bioavailability of poorly-soluble...

Drug crystal growth in ternary amorphous solid dispersions: Effect of surfactants and polymeric matrix-carriers

11. June 2021

The present study evaluates the crystal growth rate of amorphous drugs when dispersed in different ternary polymeric amorphous solid dispersions...

Exploring the Role of Surfactants in Enhancing Drug Release from Amorphous Solid Dispersions at Higher Drug Loadings

7. June 2021

To reduce the dosage size of amorphous solid dispersion (ASD)-based formulations, it is of interest to devise formulation strategies that...

Formulation of Gelucire®-Based Solid Dispersions of Atorvastatin Calcium: In Vitro Dissolution and In Vivo Bioavailability Study

29. May 2021

Atorvastatin (ATV) is a poorly water-soluble drug that exhibits poor oral bioavailability. Therefore, present research was designed to develop ATV...

graphical abstract of Ileo-Colon Targeting of the Poorly Water-Soluble Drug Celecoxib Using a pH-Dependent Coating in Combination with Self-Emulsifying Drug Delivery or Solid Dispersion Systems

Ileo-Colon Targeting of the Poorly Water-Soluble Drug Celecoxib Using a pH-Dependent Coating in Combination with Self-Emulsifying Drug Delivery or Solid Dispersion Systems

28. May 2021

Targeting celecoxib to the ileo-colonic region could be beneficial for the treatment and prevention of colon cancer. Ileo-colonic targeting can...

graphical abstract of Role of Surfactant Micellization for Enhanced Dissolution of Poorly Water-Soluble Cilostazol Using Poloxamer 407-Based Solid Dispersion via the Anti-Solvent Method

Role of Surfactant Micellization for Enhanced Dissolution of Poorly Water-Soluble Cilostazol Using Poloxamer 407-Based Solid Dispersion via the Anti-Solvent Method

13. May 2021

This study aimed to investigate the role of micellization of sodium lauryl sulfate (SLS) in poloxamer 407 (POX)-based solid dispersions...

Solid Dispersion

Impact of Matrix Surface Area on Griseofulvin Release from Extrudates Prepared via Nanoextrusion

Solid Dispersion as a Technical Solution to Boost the Dissolution Rate and Bioavailability of Poorly Water-Soluble Drugs

Continuous downstream processing of milled electrospun fibers to tablets monitored by near-infrared and Raman spectroscopy

Nanostructured micronized solid dispersion of crystalline-amorphous metronidazole embedded in amorphous polymer matrix prepared by nano spray drying

Phase behavior of ASDs based on hydroxypropyl cellulose

Drug crystal growth in ternary amorphous solid dispersions: Effect of surfactants and polymeric matrix-carriers

Exploring the Role of Surfactants in Enhancing Drug Release from Amorphous Solid Dispersions at Higher Drug Loadings

Formulation of Gelucire®-Based Solid Dispersions of Atorvastatin Calcium: In Vitro Dissolution and In Vivo Bioavailability Study

Ileo-Colon Targeting of the Poorly Water-Soluble Drug Celecoxib Using a pH-Dependent Coating in Combination with Self-Emulsifying Drug Delivery or Solid Dispersion Systems

Role of Surfactant Micellization for Enhanced Dissolution of Poorly Water-Soluble Cilostazol Using Poloxamer 407-Based Solid Dispersion via the Anti-Solvent Method

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