A novel combination of Soluplus ®/Poloxamer for Meloxicam solid dispersions via hot melt extrusion for rapid onset of action. P

A novel combination of Soluplus ®/Poloxamer for Meloxicam solid dispersions via hot melt extrusion for rapid onset of action. Part 2: comparative bioavailability and IVIVC

12. February 2021

Objective: Bioavailability of Meloxicam (MLX) from solid dispersions (SDs), against innovator product Mobic® in humans was conducted. Furthermore, to establish...

A novel combination of Soluplus® and Poloxamer for Meloxicam solid dispersions via hot melt extrusion for rapid onset of action—part 1: dissolution and stability studies

12. February 2021

The hot melt extrusion (HME) technique was proposed to prepare solid dispersions (SDs) of the high melting point meloxicam (MLX)...

multicomponent-solid-dispersion-produced-by-spray-drying

Multicomponent solid dispersion: A new generation of solid dispersion produced by spray-drying

20. April 2020

The term “multicomponent solid dispersion” is widely used in recent literature to describe solid formulations consisting of a special excipient's...

Soluplus solutions as thermothickening materials for topical drug delivery.

17. October 2018

Soluplus is a pharmaceutical excipient used primarily in the manufacture of solid dispersions. The polymer also exhibits interesting rheology in...

Overview of the different usage options of KinetiSol in Pharmaceutical Spray Drying and Hot Melt Extrusion

Expanding the Application and Formulation Space of Amorphous Solid Dispersions with KinetiSol®

5. June 2018

05. June 2018 Due to the high number of poorly soluble drugs in the development pipeline, novel processes for delivery...

Stability-Enhanced Ternary Solid Dispersions with HPMC and Soluplus

24. September 2017

24. September 2017 Abstract The aim of this study was to evaluate a novel combination of hydroxypropyl methylcellulose phthalate (HPMCP-HP-50) and Soluplus®polymers...

Dual-mechanism gastroretentive drug delivery system loaded with an amorphous solid dispersion prepared by hot-melt extrusion

6. March 2017

Abstract In the present study, we aimed to prepare a gastroretentive drug delivery system that would be both highly resistant...

Mucoadhesive amorphous solid dispersions for sustained release of poorly water soluble drugs

19. January 2017

19. January 2017 Abstract The oral delivery of mucoadhesive patches has been shown to enhance the absorption of large molecules...

Bioavailability enhancement of itraconazole-based solid dispersions produced by hot melt extrusion in the framework of the Three Rs rule

15. December 2016

15. December 2016 Abstract Solid dispersion formulations made of itraconazole (ITZ) and Soluplus® (polyethylene glycol, polyvinyl acetate and polyvinylcaprolactame-based graft...

Continuous Production of Itraconazole-based Solid Dispersions by Hot Melt Extrusion: Preformulation, Optimization and Design Space Determination

11. October 2016

The purpose of this work was to increase the solubility and the dissolution rate of itraconazole, which was chosen as...

Solid Dispersion

A novel combination of Soluplus ®/Poloxamer for Meloxicam solid dispersions via hot melt extrusion for rapid onset of action. Part 2: comparative bioavailability and IVIVC

A novel combination of Soluplus® and Poloxamer for Meloxicam solid dispersions via hot melt extrusion for rapid onset of action—part 1: dissolution and stability studies

Multicomponent solid dispersion: A new generation of solid dispersion produced by spray-drying

Soluplus solutions as thermothickening materials for topical drug delivery.

Expanding the Application and Formulation Space of Amorphous Solid Dispersions with KinetiSol®

Stability-Enhanced Ternary Solid Dispersions with HPMC and Soluplus

Dual-mechanism gastroretentive drug delivery system loaded with an amorphous solid dispersion prepared by hot-melt extrusion

Mucoadhesive amorphous solid dispersions for sustained release of poorly water soluble drugs

Bioavailability enhancement of itraconazole-based solid dispersions produced by hot melt extrusion in the framework of the Three Rs rule

Continuous Production of Itraconazole-based Solid Dispersions by Hot Melt Extrusion: Preformulation, Optimization and Design Space Determination

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