Pharma Excipients
Solids
Comparison of the liquisolid technique and co-milling for loading of a poorly soluble drug in…
Abstract
Drug loading into mesoporous carriers may help to improve the dissolution of poorly aqueous-soluble drugs. However, both preparation method and carrier properties influence loading efficiency and drug release. Accordingly, this study aimed to compare two preparation methods: formulation…
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Manufacturing classification system for oral solid dosage forms of traditional Chinese medicines(Ⅰ):…
Oral solid dosage (OSD) occupies a key position in the market of Chinese patent medicines and new traditional Chinese medicines. Processing route is the foundation for the research and development of traditional Chinese medicine OSDs. On the basis of prescriptions and preparation methods of 1 308…
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Particle circulation and coating in a Wurster fluidized bed under different geometries
Abstract
The performance of particle coating is essentially determined by the morphology and uniformity of coating shells, which significantly depend on particle circulation. In this study, the geometry of a Wurster fluidized bed is changed by regulating particle circulation port size and nozzle…
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Roquette Introduced New Chapter in Moisture Protection at CPhI 2023
Press Release
La Madeleine (France), 25th October 2023 – Roquette, a global leader in plant-based ingredients and leading provider of pharmaceutical and nutraceutical excipients, is pleased to announce the addition of three new excipient grades to its unmatched portfolio of solutions for moisture…
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Preparation of Nanosized Pharmaceutical Formulations by Dual Centrifugation
Abstract
Dual centrifugation (DC) is an innovative in-vial homogenization and in-vial nanomilling technique that has been in use for the preparation of liposomes for more than one decade. Since then, DC has continuously been developed for preparing various liposomes and other lipid nanoparticles…
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Adult Patients with Difficulty Swallowing Oral Dosage Forms: A Systematic Review of the Quantitative…
Abstract
The aim of this systematic review was to identify and critically appraise the available evidence regarding solid oral dosage forms (SODFs), e.g., tablets, and challenges regarding the oral administration of medicine to inpatients in a variety of healthcare settings such as (1) hospitals,…
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Evaluation of a Three-Fluid Nozzle Spraying Process for Facilitating Spray Drying of Hydrophilic…
Abstract
Amorphous solid dispersions (ASDs) enable formulations to improve the solubility of poorly soluble active pharmaceutical ingredients (APIs). The amorphous state is reached through the disruption of the crystalline lattice of an API resulting in an increased apparent solubility with faster…
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Investigation of Various Polymers for SLS 3D-Printing of Solid Oral Dosage Forms
Purpose
Selective laser sintering (SLS) is promising for printing oral dosage forms.
Print ranges for commonly used pharmaceutical polymers not yet established for additive manufactured medications.
Evaluate dedicated polymers for pharmaceutical applications.
Objectives…
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Oral Solids – Practical Pharmaceutics Part 2
An International Guideline for the Preparation, Care and Use of Medicinal Products
See the new book, edited by Paul Le Brun, Sylvie Crauste-Manciet, Irene Krämer, Julian Smith, Herman Woerdenbag:
Description: Practical Pharmaceutics contains essential knowledge on the preparation, quality…
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Tablet in Capsule Technology – Overview
Tablets are solid dosage forms containing medicinal substances with or without suitable diluents. They are the most widely preferred form of medication both by pharmaceutical manufacturer as well as physicians and patients. Capsules are solid dosage forms in which drug is enclosed within either a…
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