Solubility Enhancement

Abstract Enzalutamide (ENZ), marketed under the brand name Xtandi® as a soft capsule, is an androgen receptor signaling inhibitor drug actively...

Abstract Background Ritonavir is an anti-retroviral protease inhibitor to treat HIV, AIDS infections. Methods The RN-SLNs were prepared by using...

Abstract Background: Curcumin and hesperetin are plant polyphenols known for their poor solubility. To address this limitation, we prepared amorphous PVP...

Abstract Micronization is frequently employed to increase the dissolution of poorly soluble drugs, but it easily led to powder aggregation...

Sodium L-glutamate, better known as Monosodium glutamate (MSG) by Dr. Paul Lohmann® , has emerged as a crucial component in...

Abstract Curcumin (CUR), a polyphenolic pigment of turmeric, -possess biological and medicinal properties. Regardless of having a wide range of...

Abstract There is a growing pharmaceutical interest in supersaturated lipid-based formulations (Super-LbF) as an innovative strategy to enhance drug loading...

Abstract Proteins have recently caught attention as potential excipients for amorphous solid dispersions (ASDs) to improve oral bioavailability of poorly...

Abstract Oral absorption is limited for many small-molecule drugs due to their poor aqueous solubility as well as, for some,...

This poster was presented at the AAPS 2024 by APRECIA and Millipore Sigma   Many new drug substances are poorly...