Solubility Enhancement

Abstract Coenzyme Q10 (CoQ10) is a lipophilic antioxidant agent that plays a crucial role in the mitochondrial electron transport chain....

Abstract Background: Melt-based 3D printing technologies are currently extensively evaluated for research purposes as well as for industrial applications. Classical approaches...

Abstract Purpose of Review Conventional antimalarial therapies often encounter issues of drug resistance, low bioavailability, and systemic toxicity. However, recent...

Abstract Dasatinib (DASA), a potent second-generation multitarget kinase inhibitor marketed as Sprycel® (Tablet), is limited by poor oral bioavailability (14–24 %)...

Abstract Diffuse intrinsic pontine glioma (DIPG) poses a significant treatment challenge in pediatric patients due to its aggressive nature and...

Abstract Preclinical testing of new drug candidates frequently necessitates high-dose solution formulations to support robust testing in rodent models. This...

Abstract Ex vivo drug permeability testing across gastrointestinal (GI) membranes is crucial in drug discovery and oral drug delivery. It is...

Abstract Invasive pulmonary aspergillosis poses a significant threat to immunocompromised patients, characterized by high mortality rates. Posaconazole (PSZ), a second-generation...

Abstract Curcumin, a bioactive compound derived from turmeric, possesses numerous pharmaceutical properties; however, its poor aqueous solubility and permeability result...

Abstract Background: Liver fibrosis is a necessary pathological process in many chronic liver diseases. Studies have shown that the progression of...