Solubility Enhancement

Emerging and reemerging viruses pose significant public health threats, underscoring the urgent need for new antiviral drugs. Recently, a novel...

The present study aimed to develop and optimize solidified supersaturated self-nanoemulsifying drug delivery systems (SNEDDS) for the combined administration of...

This poster was presented at EuPFI 2024 in Rotterdam. Introduction Loratadine, an antihistamine medication, is widely prescribed for the treatment...

Abstract Neratinib maleate (NM) used in the treatment of breast cancer, has a low and variable oral bioavailability due to...

Abstract Twenty-five years ago, Hancock and Parks asked a provocative question: “what is the true solubility advantage for amorphous pharmaceuticals?”...

Abstract Herein, we present an elegant and simple method for significant improvement of eugenol water solubility using the polymers Soluplus® and...

Improving the solubility of poorly water-soluble drugs is essential for enhancing bioavailability, formulation flexibility and reducing patient-to-patient variability. The preparation...

EUDRAGIT® polymers can be used individually or in combination to match virtually any target release profile including immediate, delayed, sustained,...

Abstract Inflammatory Bowel Disease (IBD) is a chronic condition that affects approximately 1.6 million Americans. While current polyphenols for treating...

About 90% of active pharmaceutical ingredients (APIs) in the oral drug delivery system pipeline have poor aqueous solubility and low...