Solubility Enhancement

Multidrug-resistant tuberculosis (MDR-TB) and extensively drug-resistant tuberculosis (XDR-TB) continue as public health concerns. Inhaled drug therapy for TB has substantial...

Abstract Improvement in drug solubility is a major challenge for developing pharmaceutical products. It was demonstrated earlier that aqueous solubilities...

The phospholipids complexation technique is the best solubility enhancement technology, and as a result, many authors have successfully used it...

Abstract Background and purpose: Sorafenib tosylate (SFN), a potent multikinase inhibitor, is used for the treatment of various cancers. However, it...

Twin-screw wet granulation (TSG) is a continuous manufacturing technique either for granules as final dosage form or as an intermediate...

Abstract Background: Fenofibrate (FF) is a BCS class II compound whose poor solubility poses challenges in drug delivery and bioavailability. Solid...

Abstract The liquisolid system of drug delivery continues to find usefulness as a potent means to circumvent solubility and dissolution...

Many of the utilized drugs which already exist in the pharmaceutical sector are hydrophobic in nature. These drugs are characterized...

A significant majority of the 20 approved nanoformulations consist predominantly of nanocrystals (NCs). NCs are nanosized drug moieties comprising 100...

Chronic obstructive pulmonary disease (COPD) is a prevalent lung condition characterized by airflow obstruction, disability, and high mortality rates. Magnolol...