Solubility Enhancement

Press Release June 9, 2025 CLEVELAND, Ohio — Lubrizol announces that an Apisolex™ polymer excipient-enabled drug formulation is in Phase...

Abstract Aim Quercetin is a natural dietary compound known for its potential to prevent chronic diseases. However, the translation of...

Abstract The purpose of this study was to develop and evaluate a sublingual tablet of lercanidipine hydrochloride for the direct...

Abstract This research study aimed to develop and evaluate a novel freeze-dried nanocrystals formulation of sotorasib (AMG-510) using Quality by...

Abstract Inflammatory skin diseases are chronic conditions that significantly affect patients’ skin health and quality of life. Traditional treatments, including...

Abstract Nanotechnology has revolutionised pharmaceutical sciences, with mesoporous silica nanoparticles (MSNs) extensively studied as drug carriers. However, their clinical translation...

Abstract Ivermectin (IVM) is a widely used antiparasitic agent and has been repurposed for the treatment of COVID-19. However, its...

Abstract Lung cancer, particularly NSCLC, poses a major therapeutic challenge due to drug resistance and the poor aqueous solubility of...

Abstract Purpose Posaconazole (POS) is widely used as an antifungal agent effective against Candida infections. Because of its very low...

Abstract Most novel active pharmaceutical ingredients have low water solubility; therefore, solubility-enhancing methods are applied. The aim of the present...