Solubility Enhancement

Abstract Clofazimine (CFZ) is a highly effective antibiotic against leprosy and drug-resistant tuberculosis and is on the WHO List of...

This poster was presented at the ECP 2025 in Porto Introduction Hot melt extrusion (HME) is generally applied for the...

Abstract Background/Objectives: Curcumin has well-established efficacy in a variety of disorders due to its prominent antioxidant, antiaging, anti-inflammatory, chemosensitizing, and...

Roquette presents a new product: KLEPTOSE® F 7% - EXP β-cyclodextrin for oral dosage forms contains less than 7% of...

Abstract Ternary co-amorphous systems, comprising a drug, a low molecular weight co-former, and a polymer, are a promising approach to...

Abstract Gefitinib (GB), an oral tyrosine kinase inhibitor suffers major setbacks in clinical application due to limited aqueous solubility leading...

Abstract The solubility behavior of drugs is a critical factor in formulation development. Approximately 40–45% of new drugs face market...

This study evaluates the in vivo mucoadhesive properties of thiolated cyclodextrins (CDs) with varying S-protection using polyethylene glycol (PEG) of...

Here we designed an optimized NLC for the transport of CLP, an antiplatelet molecule, and further probed its microstructure, cytotoxicity...

Abstract Mesoporous silica carriers are known to improve the solubility and bioavailability of poorly soluble Class II drugs. However, most...