Solubility Enhancement

Abstract Amorphous solid dispersions (ASDs) make a significant contribution to enhancing the solubility of poorly soluble drugs. The incorporation of...

Abstract Lornoxicam (LOX) is (NSAID); it is a crystalline powder that ranges in color from orange to yellow and is...

Abstract Aceclofenac (ACF), a Non-Steroidal Anti-Inflammatory Drug (NSAID), is formulated with Soluplus® (SOLP) to enhance solubility and bioavailability. This study...

Abstract Recent advances in pH-responsive drug delivery systems have demonstrated their promising potential for targeted therapeutic delivery. However, challenges remain...

Abstract Ionic liquid (IL) salts of active pharmaceutical ingredients (API) represent promising formulations for poorly-soluble APIs as they eliminate polymorphism...

Abstract The present study focuses on the development and optimization of a solid self-microemulsifying drug delivery system (SSMEDDS) of Nateglinide,...

Abstract The underlying mechanisms governing amorphous solid dispersions (ASDs) stability are complex and influenced by multiple factors, making it a...

Abstract Purpose Azelaic acid (AZE) is a widely used agent in acne treatment, but its poor water solubility limits its...

Abstract Aim: In addition to numerous benefits provided by nanosuspensions (NSs) (e.g., enhanced saturation solubility, increased area for interaction with fluids),...

Abstract Poor aqueous solubility and slow dissolution rate of active pharmaceutical ingredients (APIs) are often encountered challenges during oral drug...