Solubility Enhancement

Abstract Recent advances in pH-responsive drug delivery systems have demonstrated their promising potential for targeted therapeutic delivery. However, challenges remain...

Abstract Ionic liquid (IL) salts of active pharmaceutical ingredients (API) represent promising formulations for poorly-soluble APIs as they eliminate polymorphism...

Abstract The present study focuses on the development and optimization of a solid self-microemulsifying drug delivery system (SSMEDDS) of Nateglinide,...

Abstract The underlying mechanisms governing amorphous solid dispersions (ASDs) stability are complex and influenced by multiple factors, making it a...

Abstract Purpose Azelaic acid (AZE) is a widely used agent in acne treatment, but its poor water solubility limits its...

Abstract Aim: In addition to numerous benefits provided by nanosuspensions (NSs) (e.g., enhanced saturation solubility, increased area for interaction with fluids),...

Abstract Poor aqueous solubility and slow dissolution rate of active pharmaceutical ingredients (APIs) are often encountered challenges during oral drug...

Press Release June 9, 2025 CLEVELAND, Ohio — Lubrizol announces that an Apisolex™ polymer excipient-enabled drug formulation is in Phase...

Abstract Aim Quercetin is a natural dietary compound known for its potential to prevent chronic diseases. However, the translation of...

Abstract The purpose of this study was to develop and evaluate a sublingual tablet of lercanidipine hydrochloride for the direct...