Spray drying

Introduction Within the last decades a new subgroup of diluents, so called Co-processed Excipients (CPE), found its way into pharmaceutical...

The bioavailability of rivaroxaban at the higher doses (15 and 20 mg) is considerably reduced when the drug is administered on...

This study explores the effect of spray-drying (SD) inlet temperatures (Tinlet 120 and 150 °C) and wall material on the chemical and...

Abstract Active pharmaceutical ingredients (APIs) and excipients can be carefully combined in premix-based materials before being added to dosage forms,...

Conventional spray drying using a 2-fluid nozzle forms matrix microparticles, where drug is distributed throughout the particle and may not...

Abstract The contributions of fine excipient materials to drug dispersibility from carrier-based dry powder inhalation (DPI) formulations are well acknowledged,...

Abstract Nanocrystalline cellulose (CNC) has emerged as a subject of researcher’s interest because of its diverse attributes encompassing biocompatibility, sustainability,...

Fouling reduces spray dryer operability. The impact of different configurations of a spray dryer on operability and nozzle-zone agglomeration stimulated...

Shin-Etsu supplies the various excipients for pharmaceutical industry. Let us introduce you Shin-Etsu AQOAT® Hypromellose acetate succinate (HPMCAS, NF, JP),...

This case study was presented at the 14th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, 18 - 21 March...