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abitec
Formulation of Plumbagin Loaded Microemulsion: Evaluation of Anti-rheumatoid efficacy in Wistar Rat…
Rheumatoid arthritis has become a common disease among the elderly. Plumbagin, a plant-derived chemical, has been shown to lower the levels of proinflammatory cytokines and interleukins linked to rheumatoid arthritis progression. The objective of the present research work was to assess the…
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Formulation, Optimization and Evaluation of Ticagrelor Loaded Self Microemulsifying Chewable Tablets
Ticagrelor is a new generation Adenosine diphosphate receptor inhibitor drug which is highly lipohilic having poor aqueous solubility used in the treatment of Acute Coronary Syndrome and prevention of Thrombotic events like Stroke and Heart Attack. An approach has been made to develop Chewable…
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Three-Dimensional Printing of a Container Tablet: A New Paradigm for Multi-Drug-Containing Bioactive…
This research demonstrates the use of fused deposition modeling (FDM) 3D printing to control the delivery of multiple drugs containing bioactive self-nano emulsifying drug-delivery systems (SNEDDSs). Around two-thirds of the new chemical entities being introduced in the market are associated with…
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The impact of quantity of lipid based formulations with different compositions on the oral…
In this study, the effect of the quantity of lipid-based formulations (LBFs) on the oral absorption of ritonavir (RTV), a model for poorly water-soluble drugs, was investigated. Two types of LBFs, comprising short- and medium-chain lipids (LBF-SMC) and long-chain lipids (LBF-LC) loaded with…
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Topical Nanoemulgel for the Treatment of Skin Cancer: Proof-of-Technology
The present study is a mechanistic validation of ‘proof-of-technology’ for the effective topical delivery of chrysin nanoemulgel for localized, efficient treatment of melanoma-affected skin.
Background: Currently available treatments for skin cancer are inefficient due to systemic side effects…
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3D-printing of solid lipid tablets from emulsion gels
Interest in 3D-printing technologies for pharmaceutical manufacturing of oral dosage forms is driven by the need for personalized medicines. Most research to date has focused on printing of polymeric-based drug delivery systems at high temperatures. Furthermore, oral formulation development is…
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Formulation and Optimization of Fluvastatin Loaded Self-emulsifying Drug Delivery Systems
Abstract-Introduction: The current research is aimed at formulating and evaluating fluvastatin self-nanoemulsifying drug delivery system (SNEDDS).
Materials and Methods: Fluvastatin SNEDDS formulated using sefsol-218 (oil), Cremophor RH40 (surfactant), and propylene glycol…
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Formulation Development and In Vitro Evaluation of Curcumin-Loaded Solid Self-Nanoemulsifying Drug…
Objective: Cancer is the deadliest disease affecting the life of the people all around the world. Colon cancer is the cancer which is affecting the colon region it is the last part of the gastrointestinal tract which is mainly responsible for the absorption of water and minerals from the food…
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Carvedilol loaded SMEDDS
Solidification of carvedilol loaded SMEDDS by swirling fluidized bed pellet coating
Self-(micro)emulsifying drug delivery systems (S(M)EDDS) have emerged as effective vehicles for enhancing bioavailability of poorly water soluble drugs, however solidification of the systems represents a major…
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