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Diclofenac sodium was used as a model drug for preparation of delayed-release (DR) multiparticulates, which were further processed into solid...
Highlights • Twin-screw granulation was less sensitive for liquid amount used. • API compaction properties had only minor effect on...
Evolution of the compaction properties of powders with the compaction speed (strain rate sensitivity, SRS) is a common phenomenon during...
This study focuses on the impact of initial particle size on the tabletability and the deformation behaviour (i.e. plasticity) of...
Drug layering on starter pellets is a standard technology to achieve multiparticulate dosage forms. The most widely used are still...
The effect of a wide variety of binders on the quality of granules produced via continuous twin screw wet granulation...
Sensitivity to a stress concentration is important for the development of pharmaceutical tablets as it is related to defects like...
Isomalt is a polyol derived from sucrose. Advantages of this excipient are its sweet taste, which is supposed to allow...
Rutin is one of the most important flavonoids with poor bioavailability. This work aimed at addressing the issue of poor...
Influence of the compaction speed on the final tablet properties is an important challenge during the scale-up of a solid...
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