Captisol

SBECD (Captisol®) with an average degree of substitution of 6.5 sulfobutylether functional groups (SBE = 6.5), is a solubility enhancer...

Bosentan is choice of drug for pulmonary arterial hypertension. It belongs to BCS class-II category. Due to poor solubility in...

Oral delivery of nanoparticles possesses many advantages for delivery of active pharmaceutical ingredients (APIs) to the gastrointestinal tract. However, the poor physical...

Pathogenic bacteria use quorum sensing (QS), a cell-to-cell communication process that uses small signalling molecules, to regulate several essential virulence...

Cefixime (CEF) is a cephalosporin included in the WHO Model List of Essential Medicines for Children. Liquid formulations are considered...

Genistein (GT) is a poorly water-soluble flavonoid and reported for different biological activity. The present work was designed to prepare...

The dearth of new medicines effective against antibiotic-resistant bacteria presents a growing global public health concern1. For more than five...

Microphysiological in vitro systems are platforms for preclinical evaluation of drug effects and significant advances have been made in recent...

Levofloxacin (LVF) is an antibacterial drug approved for the treatment of ocular infections. However, due to the low ocular bioavailability,...

This study was aimed to evaluate the impact of water-soluble β-cyclodextrin polymer (β-CDP), as a nanocarrier, on the therapeutic efficacy of...