Formulation of ternary genistein β-cyclodextrin inclusion complex: In vitro characterization and cytotoxicity assessment using

Formulation of ternary genistein β-cyclodextrin inclusion complex: In vitro characterization and cytotoxicity assessment using breast cancer cell line

11. November 2021

Genistein (GT) is a poorly water-soluble flavonoid and reported for different biological activity. The present work was designed to prepare...

Fig. 3 - Structure of IBX in complex with the 70S ribosome, mRNA and tRNAs

A synthetic antibiotic class overcoming bacterial multidrug resistance

3. November 2021

The dearth of new medicines effective against antibiotic-resistant bacteria presents a growing global public health concern1. For more than five...

Tumour-on-chip microfluidic platform for assessment of drug pharmacokinetics and treatment response

29. August 2021

Microphysiological in vitro systems are platforms for preclinical evaluation of drug effects and significant advances have been made in recent...

Development of Chitosan/Cyclodextrin Nanospheres for Levofloxacin Ocular Delivery

27. August 2021

Levofloxacin (LVF) is an antibacterial drug approved for the treatment of ocular infections. However, due to the low ocular bioavailability,...

Enhancing in vitro cytotoxicity of doxorubicin against MCF-7 breast cancer cells in the presence of water-soluble β-cyclodextrin polymer as a nanocarrier agent

16. February 2021

This study was aimed to evaluate the impact of water-soluble β-cyclodextrin polymer (β-CDP), as a nanocarrier, on the therapeutic efficacy of...

Investigation of hydroxypropyl-β-cyclodextrin inclusion complexation of two poorly soluble model drugs and their taste-sensation – Effect of electrolytes, freeze-drying and incorporation into oral film formulations

22. December 2020

The goal for any formulation design of poorly soluble drugs is to increase the solubility. However, increased solubility is a...

graphical abstract of Synthesis of cyclodextrin-derived star poly(N-vinylpyrrolidone)/poly(lactic-co-glycolide) supramolecular micelles via host-guest interaction for delivery of doxorubicin

Synthesis of cyclodextrin-derived star poly(N-vinylpyrrolidone)/poly(lactic-co-glycolide) supramolecular micelles via host-guest interaction for delivery of doxorubicin

4. December 2020

Supramolecular micelles are of particular interest in cancer therapy, owing to their capability to enable the on-demand drug release in...

Ligand’s Captisol Technology Plays Key Role In The Manufacture Of Gilead’s Veklury, The First FDA-Approved Covid-19 Treatment

19. November 2020

SAN DIEGO--(BUSINESS WIRE) -- Ligand Pharmaceuticals Incorporated (NASDAQ: LGND) today highlighted the company’s role in the manufacturing of Veklury® (remdesivir), Gilead...

SEM photomicrographs of cilostazol Pellets

Fabrication and evaluation of fast disintegrating pellets of cilostazol

12. October 2020

The present study was designed to formulate and develop fast disintegrating pellets of poorly soluble model drug (cilostazol) by reducing...

Development of Remdesivir as a Dry Powder for Inhalation by Thin Film Freezing

23. September 2020

Remdesivir exhibits in vitro activity against SARS-CoV-2 and was granted approval for Emergency Use. To maximize delivery to the lungs,...

Captisol

Formulation of ternary genistein β-cyclodextrin inclusion complex: In vitro characterization and cytotoxicity assessment using breast cancer cell line

A synthetic antibiotic class overcoming bacterial multidrug resistance

Tumour-on-chip microfluidic platform for assessment of drug pharmacokinetics and treatment response

Development of Chitosan/Cyclodextrin Nanospheres for Levofloxacin Ocular Delivery

Enhancing in vitro cytotoxicity of doxorubicin against MCF-7 breast cancer cells in the presence of water-soluble β-cyclodextrin polymer as a nanocarrier agent

Investigation of hydroxypropyl-β-cyclodextrin inclusion complexation of two poorly soluble model drugs and their taste-sensation – Effect of electrolytes, freeze-drying and incorporation into oral film formulations

Synthesis of cyclodextrin-derived star poly(N-vinylpyrrolidone)/poly(lactic-co-glycolide) supramolecular micelles via host-guest interaction for delivery of doxorubicin

Ligand’s Captisol Technology Plays Key Role In The Manufacture Of Gilead’s Veklury, The First FDA-Approved Covid-19 Treatment

Fabrication and evaluation of fast disintegrating pellets of cilostazol

Development of Remdesivir as a Dry Powder for Inhalation by Thin Film Freezing

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