Dupont Pharma

Abstract The pharmaceutical industry is currently moving away from traditional approaches to quality control with off-line quality tests, limited in-line...

Abstract Pharmaceutical tablet formulation and process development, traditionally a complex and multi-dimensional decision-making process, necessitates extensive experimentation and resources, often...

Abstract Background/Objectives: The oral delivery of large-molecule drugs remains challenging due to poor solubility, perdemeability, and stability in the gastrointestinal...

Abstract Nanocellulose, a sub-micron cellulose powder, was investigated as a potential filler excipient to enhance the tabletability of acetaminophen (APAP)....

Abstract This study leverages Fourier Transform Near-Infrared (FT-NIR) spectroscopy to monitor the coating process of pharmaceutical tablets using PVA-based TiO2-free...

Abstract Although the development of extended release (ER) matrices has been extensively investigated, understanding the most appropriate mechanism of drug...

Abstract This study investigates the simultaneous prediction of active pharmaceutical ingredient (API) concentration and mass gain in film-coated tablets using...

Abstract Atomic layer coating (ALC) is an emerging, solvent-free technique to coat amorphous solid dispersion (ASD) particles with a nanolayer...

Abstract Amorphous solid dispersion (ASD) tablets based on hydrophilic polymer carriers may encounter disintegration challenges. In this work, the effect...

Abstract Fluidized bed granulation is a single unit operation that integrates several process transformations including powder transfer and fluidization, atomization...