A hybrid polymeric system for pulmonary mRNA delivery: Advancing mucosal vaccine development

22. January 2026

Highlights PLGA/PBAE coordinates endosomal escape and timely mRNA release in APCs PLGA/PBAE enhances mRNA transfection in APCs and promotes immune...

Leveraging complementary functions of hydroxypropyl methylcellulose and croscarmellose sodium to develop gastroretentive tablets via predictive regression-based modeling

19. January 2026

Abstract We report gastroretentive (GR) tablets optimized via a data-driven regression-based predictive modeling strategy to determine the optimal hydroxypropyl methylcellulose...

Simultaneous evaluation of drug absorption and in vivo release behavior from coated mini tablets with Eudragit L 30 D-55 in rats using near-infrared imaging

15. January 2026

We previously demonstrated the use of near-infrared (NIR) imaging to evaluate differences in disintegration for various capsule formulations after oral...

Fabrication and characterization of taste-masked core-shell nanofibre mats for dual drug delivery of antihypertensives in pediatrics

9. January 2026

Abstract Drug adherence in pediatrics can be challenging due to bitter drug taste, dysphagia and polypharmacy. With pediatric hypertension on...

Polymeric Nanocapsules Containing Kojic Acid Dipalmitate and Rosehip Oil: Development and Evaluation of Preliminary Efficacy and Safety for Skin Whitening

28. December 2025

Polymeric nanocapsules associated with kojic acid dipalmitate (KDP) and rosehip oil can be a strategy to obtain high-performance skin whitening/lightning...

3D-Printed Multifunctional Multicompartment Polymer-Based Capsules for Tunable and Spatially Controlled Drug Release

26. December 2025

Abstract The development of polymer-based systems is central to the design of next-generation drug delivery carriers, as polymers enable versatile...

High-Throughput Screening of Amorphous Solid Dispersions: A Systematic Approach to Enhance Bioaccessibility of a Poorly Soluble Drug

25. December 2025

Abstract Poor aqueous solubility and thereby poor and/or variable bioavailability of drug candidates is frequently overcome by developing enabling formulations...

Design, Optimization And In-Vitro–Ex-Vivo Evaluation Of Enteric-Coated Nanocarriers For Enhanced Oral Bioavailability Of A Poorly Soluble Drug

15. December 2025

Abstract The present study aimed to design, optimize, and evaluate enteric-coated nanocarriers to enhance the oral bioavailability of Rifaximin, a...

Twin-screw melt granulation of Eudragit® FS100: optimization of coating-free delayed-release matrix tablets with HPMC K4M modulation

12. November 2025

Abstract This study aimed to develop a scalable, coating-free delayed-release matrix tablet via twin-screw melt granulation (TSMG) using Eudragit® FS100...

Excipients at AAPS 2025: Comprehensive Overview of Innovation in Formulation and Drug Delivery

8. November 2025

The AAPS Annual Meeting 2025 is happening November 9-12, 2025, at the Henry B. Gonzalez Convention Center in San Antonio,...

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