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Abstract Microcrystalline cellulose (MCC) is extensively used in pharmaceutical formulations due to its exceptional functionality as a diluent, dry binder, disintegrant, and absorbent. Despite being marketed in numerous grades that vary in particle size, source, extraction techniques, and…
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Abstract Vaginal drug delivery has gained significant interest due to its numerous advantages, such as good blood flow, bypassing the first-pass effect, low systemic side effects, and potential for sustained release of pharmaceuticals. Initially targeting contraception and local effects from…
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Abstract Recent advances in pH-responsive drug delivery systems have demonstrated their promising potential for targeted therapeutic delivery. However, challenges remain in developing platforms that combine precise spatiotemporal control with robust mechanical properties. Herein, we present a novel…
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Abstract Ionic liquid (IL) salts of active pharmaceutical ingredients (API) represent promising formulations for poorly-soluble APIs as they eliminate polymorphism commonly associated with conventional API salts. Being highly viscous liquid, oral dosage formulation of API-ILs is challenging,…
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Abstract The present study focuses on the development and optimization of a solid self-microemulsifying drug delivery system (SSMEDDS) of Nateglinide, a poorly water-soluble antidiabetic drug, to enhance its oral bioavailability. Initially, a liquid SMEDDS was formulated using Capmul MCM as the…
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The following poster was presented at IPEC Americas Excipient World 2025: PURPOSE Sodium alginate, a naturally occurring polysaccharide, serves as a widely utilized pharmaceutical excipient owing to its biocompatibility, biodegradability, non-toxicity, gelling attributes, and capacity to form gels…
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Abstract Background: Modification of commercially available medicine, e.g. splitting or dissolving of tablets or pharmacy compounding, is current clinical practice when desired oral dosage forms are unavailable. These practices are defined as conventional pharmacy compounding techniques and are…
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Streamline Your R&D and Production Introduction The health science industry faces a wide variety of challenges including increased pressure to: Reduce costs Accelerate time to market Improve product performance Cope with high demands and tight capacities Utilize modern…
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Abstract Background/Objectives: In this study, we present a green, scalable platform for the production of water-dispersible powders co-encapsulating the lipophilic bioactives curcumin (Cur) and eugenol (Eug) within the amphiphilic polymer Soluplus® (SP) via low-temperature spray drying.…
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Abstract The application of artificial neural networks (ANNs) has the potential to fundamentally change the pharmaceutical industry, making manufacturing more agile, robust, efficient and reliable. Although ANNs’ application as data-driven soft sensors has a particular potential, the black-box…
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