PMC Isochem

ABSTRACT Objectives Novel D-α-tocopherol polyethylene glycol 1000 succinate (TPGS) modified lipid nanocapsules (LNC) were prepared with the aim of improving...

The management of Alzheimer's disease (AD) remains challenging owing to its complex pathophysiology and blood-brain barrier (BBB) restrictions. A rationally...

Nowadays, conventional anticancer therapy suffers many pitfalls, including drastic side effects and limited therapeutic efficacy resulting from diminished oral bioavailability....

HIV/AIDS remains a major global public health issue. While antiretroviral therapy is effective at reducing the viral load in the...

Lung cancer is currently the most prevalent cause of cancer mortality due to late diagnosis and lack of curative therapies....

Solid dispersions (SDs) of ursolic acid (UA) were developed using polyvinylpyrrolidone K30 (PVP K30) in combination with non-ionic surfactants, such...

Natural medicines are promising platforms for competent topical treatment modalities benefiting the cosmetic implementation and proffering solutions to the current...

To improve the solubility and maintain the amorphous state of BCS Ⅳ drug by preparing surfactant solid dispersions, solid dispersions...

It has been seventy years since a water-soluble version of vitamin E called tocophersolan (also known as TPGS) was produced;...

Formulations based on emulsions for enhancing hydrophobic and lipophilic drug delivery and its bioavailability have attracted a lot of interest....