PMC Isochem

Abstract Pterostilbene is a highly researched molecule due to its bioactivity. However, its hydrophobicity limits its application. For this reason,...

Solid lipid-based formulations (sLBFs) have the potential to increase the oral bioavailability of drugs with poor solubility in water, while...

Binary co-amorphous systems (CAMS) are a type of solid dispersion containing an active pharmaceutical ingredient (API) and small molecule excipients....

Transdermal drug delivery is an alternative route of administration that offers avoidance of the associated drawbacks of orally and parenterally...

Tocophersolan (D-α-tocopheryl polyethylene glycol succinate or TPGS) is a non-ionic surfactant fabricated by esterifying Vitamin E succinate with polyethylene glycol....

Novel d-α-tocopheryl polyethylene glycol 1000 succinate (TPGS) micelles containing the anti-cancer drug artesunate (ART) were developed in a dry powder...

The poor aqueous solubility is a well-recognized restriction for the clinical application of many drug molecules. Micelles delivery system provides...

HIV/AIDS remains a major global public health issue. While antiretroviral therapy is effective at reducing the viral load in the...

The treatment of several ocular inflammatory conditions affecting different areas of the ocular globe involves the administration of topical ophthalmic...

Despite many efforts to improve the transdermal permeability of drugs, most of them are blocked by the skin barrier. Niacinamide...