PMC Isochem

The paediatric population has always suffered from a lack of medicines tailored to their needs, especially in terms of accurate...

Self-nanoemulsifying drug delivery systems (SNEDDS) represent an interesting platform for improving the oral bioavailability of poorly soluble lipophilic drugs. While...

Purpose: The present study aimed to develop gefitinib-loaded solid lipid nanoparticles (GEF-SLN), and GEF-loaded PEGylated SLN (GEF-P-SLN) for targeting metastatic lung...

Ursolic acid (UA) solid dispersions (SD) formulated into poloxamer-hydrogels were prepared for local treatment of skin inflammations. The hydrogel physico-chemical properties...

D-tocopheryl polyethylene glycol succinate (Vitamin E TPGS) has been approved as a safe pharmaceutical adjuvant by FDA, and several drug...

Topical drug delivery provides several benefits over other conventional routes by providing localizing therapeutic effects and also avoids the gastrointestinal...

Still today, high-concentration protein formulations are often developed based on high-throughput experimental screening approaches. Although likely delivering working formulations, these...

Herein, a series of vitamin E-based TPGS-poly(2-(dimethylamino)ethyl methacrylate)-b-poly(3-vinyl benzaldehyde) block copolymer micelles were synthesized via reversible addition−fragmentation chain-transfer polymerization (RAFT). d-α-tocopheryl poly(ethylene glycol) 1000 succinate (TPGS)...

Efflux transporters distributed at the apical side of human intestinal epithelial cells actively transport drugs from the enterocytes to the...

Manganese-zinc ferrite (MZF) is known as high-performance magnetic material and has been used in many fields and development. In the...