Direct Compression

The characterization of pharmaceutical powders by means of the SeDeM diagram expert system allows developing a database. This database is a useful tool in pre-formulation steps as initial screening for suitable filler excipients. This study compiles the characterization of 21 powdery…
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The pharmaceutical tablet formulation design is a risky and challenging process since it largely depends on experience. The fundamental reasons lie in the lack of understanding of powder properties and the interactions between the active pharmaceutical ingredients and excipients. To compensate these…
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Cashew gum is extracted from the exudate of the giant cashew tree (Anacardium occidentale L.). The objective of this work was to study the extraction and purification of cashew gum through experiments to characterize its structures and physicochemical and thermal properties, and to evaluate its use…
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13. September 2018 Herein we introduce an innovative process for preparation of directly compressible API and excipient agglomerates for extended release formulation of a highly water soluble drug, demonstrated with metformin HCl. Metformin is poorly compressible and currently employs wet…
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