Tag: formulation

Abstract The most relevant challenge concerning the semi-solid extrusion 3D printing (SSE) pharmaceutical application is the development of versatile inks ...

Abstract Oral bioavailability (%F) is a key determinant of drug efficacy and a critical decision-making parameter in early-stage drug development. ...

The promise of oral biologics continues to drive innovation across the pharmaceutical industry.  While permeation enhancement remains critical for successful ...

Abstract Nanoemulsions are increasingly explored to enhance dermal drug delivery due to their nano-size. Microfluidic processing for nanoemulsion generation has ...

Abstract Microneedles represent a novel transdermal drug delivery technology that relies on micron-sized needle structures. This approach effectively penetrates the ...

Abstract Porous silicates have been investigated as drug carriers to promote the solubility and in vitro dissolution of poorly water-soluble ...

Abstract This study presents a Quality by Design (QbD) strategy combined with Design of Experiments (DoE) to develop hybrid polymer–lipid hot-melt extruded (HME) formulations ...

Abstract Spray-freeze drying (SFD) is a promising drying technique for stabilizing RNA lipid nanoparticles (RNA-LNPs) by converting them into solid-state ...

Abstract Background A dihydrofolate reductase inhibitor, pyrimethamine has an emerging anticancer potential but is not well soluble in aqueous and ...

Abstract Bio-adhesive buccal-delivery of drugs is one of alternative to the oral route of drug administration, particularly drugs that are ...