Browsing Tag

Solubility

Merck wins CPhI Award with Parteck® MXP for Excellence in Pharmaceutical Excipients

Oct 10, 2018

We congratulate Merck for winning the Award with Parteck® MXP excipient for hot melt extrusion. Here some information on the product: Enhanced API Solubility and Stable, High Drug LoadsPoor solubility of APIs is a critical challenge in drug development. One formulation technique to address this…
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Solubilizer

The influence of polymer excipients on the dissolution and recrystallization behavior of…

Oct 2, 2018

The formulation of amorphous solid dispersions (ASDs) is an effective way to improve the bioavailability of poorly water-soluble active pharmaceutical ingredients (APIs). The combination of an amorphous state of the drug and the presence of crystallization-inhibiting polymers retains a high amount…
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Cellulose

Impact of method of preparation of Amorphous Solid Dispersions on Mechanical Properties: Comparison…

Sep 26, 2018

Usage of the amorphous phase of compounds has become the method of choice to overcome oral bioavailability problems related to poor solubility. Due to the unstable nature of glasses, it is clear that the method preparation of the amorphous glass will have an impact on physical/chemical stability…
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