Merck wins CPhI Award with Parteck® MXP for Excellence in Pharmaceutical Excipients

We congratulate Merck for winning the Award with Parteck® MXP excipient for hot melt extrusion. Here some information on the product:

Enhanced API Solubility and Stable, High Drug Loads

The influence of polymer excipients on the dissolution and recrystallization behavior of ketoconazole

Impact of method of preparation of Amorphous Solid Dispersions on Mechanical Properties: Comparison of co-precipitation and spray drying

Poor solubility of APIs is a critical challenge in drug development. One formulation technique to address this challenge is hot melt extrusion (HME). Our new Parteck® MXP is a polyvinyl alcohol-based excipient designed for hot melt extrusion to increase solubility and allow for stable and high drug loads for a broad range of APIs. The polymer has a long safety record related to its usage in drugs and is generally recognized as safe (GRAS) by the U.S. Food and Drug Administration. Parteck® MXP complies with USP, Ph. Eur., and JPE monographs.