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Abstract This study investigated the influence of solvent casting and hot-melt extrusion manufacturing methods on the physical, chemical, and functional...
Abstract Prostate cancer is the most common malignancy in men worldwide and docetaxel (DTX) is the treatment of choice. However,...
Abstract Background/Objectives: Curcumin (CUR) is a natural compound with notable antitumor properties but faces limitations in topical applications due to...
Abstract The current study includes the design of soluplus stabilized, lipid-coated, and fucoidan-oleylamine conjugate modified paclitaxel nanocrystals. The nanocrystals (Lipid-NCs)...
Abstract Poor water solubility remains a significant challenge in the pharmaceutical industry that limits the therapeutic efficacy and bioavailability of...
Abstract Pharmaceutical excipients such as P-glycoprotein inhibitors can also increase the solubility and affinity of drugs to the intestinal membrane,...
Abstract Nanocrystalline formulations typically contain stabilizing additives to minimize the risk of particle growth or agglomeration. This risk is particularly...
Abstract Lung cancer ranks among the leading factors behind cancer-related fatalities across the globe. Erlotinib (ERT) is one of the...
Abstract Purpose Ovarian cancer (OC) is difficult to detect early; therefore, it is highly likely to advance to peritoneal metastasis...
Abstract Poor solubility of many drugs, with ensuing low bioavailability, is a big challenge in pharmaceutical development. Nanosuspensions have emerged...
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